PROTAC GPX4 degrader-3

PROTAC GPX4 degrader-3

• UNSPSC Description: PROTAC GPX4 degrader-3 is a potent PROTAC GPX4 degrader with a DC50 (24h) of 0.019 μM and an IC50 of 0.024 μM in HT1080 cell[1].
• Target Antigen: Ferroptosis; PROTACs
• Type: Reference compound
• Related Pathways: Apoptosis;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-gpx4-degrader-3.html
• Smiles: O=C(OC)[C@@H](C1)N(C(CCl)=O)[C@@H](C2=CC=C(C(NCCCCCCCNC(CC3(C[C@@H](C4)C5)C[C@@H]5C[C@@H]4C3)=O)=O)C=C2)C6=C1C7=CC=CC=C7N6
• Molecular Weight: 715.32
• References & Citations: [1]Ning Y, et al. Design, synthesis, and biological evaluation of RSL3-based GPX4 degraders with hydrophobic tags. Eur J Med Chem. 2024 Jul 27;277:116719.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported