PROTAC SOS1 degrader-3
CAT:
804-HY-152145
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PROTAC SOS1 degrader-3
- CAS Number: 3029320-99-5
- UNSPSC Description: PROTAC SOS1 degrader-3 is a potent PROTAC SOS1 degrader. PROTAC SOS1 degrader-3 effectively targeted SOS1 for degradation through the ubiquitin-proteasome system[1].
- Target Antigen: PROTACs; Ras
- Type: Reference compound
- Related Pathways: GPCR/G Protein;MAPK/ERK Pathway;PROTAC
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/protac-sos1-degrader-3.html
- Solubility: 10 mM in DMSO
- Smiles: NC1=CC(C(F)(F)F)=CC([C@H](NC2=C3C=C(OC)C(OCC(NC4=CC=CC(C5=O)=C4CN5C(C(N6)=O)CCC6=O)=O)=CC3=NC(C)=N2)C)=C1
- Molecular Weight: 691.66
- References & Citations: [1]Yujia Bian, et al. Development of SOS1 Inhibitor-Based Degraders to Target KRAS-Mutant Colorectal Cancer. J Med Chem. 2022 Dec 22;65(24):16432-16450.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported