MK-8133

• UNSPSC Description:

  MK-8133 is an orexin-2 receptor antagonist. MK-8133 can be used in the study of insomnia[1].

• Target Antigen:

  Orexin Receptor (OX Receptor)

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/mk-8133.html

• Smiles:

  N#CC1=CC(O[C@H]2CN(C(C3=CC=CC=C3C4=NC=CC=N4)=O)[C@H](C)CC2)=NC=C1

• Molecular Weight:

  399.45

• References & Citations:

  [1]Kuduk SD, et al. Identification of MK-8133: An orexin-2 selective receptor antagonist with favorable development properties. Bioorg Med Chem Lett. 2015 Jun 15;25(12):2488-92.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1431472-56-8