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MK-8133

CAT: 0804-HY-123737Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-123737Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MK-8133 is an orexin-2 receptor antagonist. MK-8133 can be used in the study of insomnia[1].
CAS Number
1431472-56-8
UNSPSC
12352005
Target
Orexin Receptor (OX Receptor)
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mk-8133.html
Smiles
N#CC1=CC(O[C@H]2CN(C(C3=CC=CC=C3C4=NC=CC=N4)=O)[C@H](C)CC2)=NC=C1
Molecular Formula
C23H21N5O2
Molecular Weight
399.45
References & Citations
[1]Kuduk SD, et al. Identification of MK-8133: An orexin-2 selective receptor antagonist with favorable development properties. Bioorg Med Chem Lett. 2015 Jun 15;25 (12) :2488-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
OX2 Receptor

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