RM 49 | Gentaur

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RM 49

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804-HY-120436

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RM 49

CAS Number: 113785-48-1
UNSPSC Description: RM 49 is the derivative of Mitomycin C (HY-13316). RM 49 exhibits cytotoxicity in SCLC and NSCLC lung cancer cells with IC50 of 0.01-0.5 μg/mL. RM 49 exhibits high relative antitumor activity in compared with Mitomycin C, Cisplatin (HY-17394), Carboplatin (HY-17393) and Doxorubicin (HY-15142)[1].
Target Antigen: Others
Type: Reference compound
Related Pathways: Others
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/rm-49.html
Smiles: O=NC1=C(C2=C(C(OC)=C1C)N3[C@@](OC)([C@@H]2COC(N)=O)[C@H]4N[C@H]4C3)O
Molecular Weight: 364.35
References & Citations: [1]Horiuchi N, et al., In vitro antitumor activity of mitomycin C derivative (RM-49) and new anticancer antibiotics (FK973) against lung cancer cell lines determined by tetrazolium dye (MTT) assay. Cancer Chemother Pharmacol. 1988;22(3):246-50.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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