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RM 49

CAT: 0804-HY-120436Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120436Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RM 49 is the derivative of Mitomycin C. RM 49 exhibits cytotoxicity in SCLC and NSCLC lung cancer cells with IC50 of 0.01-0.5 μg/mL. RM 49 exhibits high relative antitumor activity in compared with Mitomycin C, Cisplatin (HY-17394), Carboplatin (HY-17393) and Doxorubicin (HY-15142).
CAS Number
113785-48-1
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rm-49.html
Smiles
O=NC1=C(C2=C(C(OC)=C1C)N3[C@@](OC)([C@@H]2COC(N)=O)[C@H]4N[C@H]4C3)O
Molecular Formula
C16H20N4O6
Molecular Weight
364.35
References & Citations
[1]Horiuchi N, et al., In vitro antitumor activity of mitomycin C derivative (RM-49) and new anticancer antibiotics (FK973) against lung cancer cell lines determined by tetrazolium dye (MTT) assay. Cancer Chemother Pharmacol. 1988;22 (3) :246-50.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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