Bcl-2-IN-10

Bcl-2-IN-10

• CAS Number: 2773354-28-0
• UNSPSC Description: Bcl-2-IN-10 is an active Bcl-2 inhibitor that can release up to four nitric oxide (NO) molecules. Bcl-2-IN-10 has cytotoxic activities against cancer cells, such as human leukemia, breast cancer and lung cancer. Bcl-2-IN-10 induces cell apopotosis and arrest cell cycle of G2/M phase, and can be used in cancer-related research[1].
• Target Antigen: Apoptosis; Bcl-2 Family
• Type: Reference compound
• Related Pathways: Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/bcl-2-in-10.html
• Solubility: 10 mM in DMSO
• Smiles: O=[N+](C1=CC([N+]([O-])=O)=C(C=C1)O/N=[N+](N2CCC(CC2)CN3CCN(CC3)/N=[N+](OC4=C(C=C(C=C4)[N+]([O-])=O)[N+]([O-])=O)\[O-])\[O-])[O-]
• Molecular Weight: 635.50
• References & Citations: [1]Xun Ji, et al. Double-component diazeniumdiolate derivatives as anti-cancer agents. Bioorg Med Chem. 2020 Apr 15;28(8):115405.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported