Caspase 2 Activity Assay Kit (Colorimetric Method)
CAT:
763-E-CK-A382-01
Size:
20 Assays
For Laboratory Research Only. Not for Clinical or Personal Use.
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No


Caspase 2 Activity Assay Kit (Colorimetric Method)
Type:
Apoptosis / CaspaseDetection Method:
Colorimetric methodAssay Principle:
Caspase 2, also known as Ich-1 (ICE and CED-3 homolog 1) or Nedd-2, can be activated during signal transduction of apoptosis. Caspase 2 mRNA can be cleaved into two different forms. The mRNA product of full-length caspase 2 can be promote apoptosis, while the protein product of short mRNA can inhibit apoptosis. Caspase 2 can be activated by caspase 1, caspase 3 and granzyme B in vitro. This caspase 2 activity assay kit is based on caspase 2 that can catalyze the substrate Ac-VDQQD-pNA to generate yellow pNA (p-Nitroaniline) . The pNA has a strong absorption near 405 nm, The activity of caspase 2 can be calculated by determining the absorbance at 405 nm.Assay Performance Time:
4 - 6 HoursSample Type:
Cell and tissue samplesShipping Conditions:
Ice BagStorage Conditions:
This product can be stored at -20°C for 12 months with shading light.Detection Instrument:
SpectrophotometerResult Type:
Qualitative or quantitative