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P53 Activator 5

CAT: 0804-HY-148404-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-148404-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
P53 Activator 5 (compound 134A) is a potent p53 activator with a SC150 value of [1]. p53 Activator 5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
2636840-37-2
UNSPSC
12352005
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p53-activator-5.html
Purity
98.43
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=CC(C(F)(F)F)=CC=C1NCC#CC2=CC3=C(C=CC=C3N[C@@H](CC4)CC[C@H]4N(C)C)N2CC(F)(F)F
Molecular Formula
C29H32F6N4O
Molecular Weight
566.58
References & Citations
[1]VU, Binh, et al. Methods and compounds for restoring mutant p53 function, WO2021061643.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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