P53 Activator 8

• Description:

  P53 Activator 8 (compound 5) is a p53 activator. p53 Activator 8 has potent anti-proliferative activity against MCF7 breast cancer cell lines with an IC50 value of 0.5 μM[1][2].

• UNSPSC:

  12352005

• Target:

  MDM-2/p53

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/p53-activator-8.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=C(CO)C(CO)=C2N1[C@H](C3=CC=CC=C3)SC2

• Molecular Formula:

  C15H17NO2S

• Molecular Weight:

  275.37

• References & Citations:

  [1]ATAÍDE SARAIVA, et al. WO2019243906. 2019.|[2]Maria I L Soares, et al. Chiral 6,7-bis (hydroxymethyl) -1H,3H-pyrrolo[1,2-c]thiazoles with anti-breast cancer properties. Eur J Med Chem. 2013.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1426937-93-0]