SC-51316

• Description :

  SC-51316 is an oral active angiotensin II receptor antagonist with the IC50 values of 3.6 and 5.1 nM in rat adrenal cortical and rat uterine membrane, respectively. SC-51316 shows antihypertensive activity in vivo and in vitro[1][2].

• CAS Number :

  [133690-62-7]

• UNSPSC :

  12352005

• Target :

  Angiotensin Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/sc-51316.html

• Smiles :

  O=C1N(CCCC)N=C(CCCC)N1CC2=CC=C(C3=C(C4=NN=NN4)C=CC=C3)C=C2

• Molecular Formula :

  C24H29N7O

• Molecular Weight :

  431.53

• References & Citations :

  [1]Olins GM, et al. In vitro pharmacology of a nonpeptidic angiotensin II receptor antagonist, SC-51316. J Pharmacol Exp Ther. 1992;261 (3) :1037-1043. |[2]Olins GM, et al. In vivo pharmacology of SC-51316, a nonpeptidic angiotensin II receptor antagonist. Am J Hypertens. 1993;6 (7 Pt 1) :619-625.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported