SC-51316

• Description:

  SC-51316 is an oral active angiotensin II receptor antagonist with the IC50 values of 3.6 and 5.1 nM in rat adrenal cortical and rat uterine membrane, respectively. SC-51316 shows antihypertensive activity in vivo and in vitro[1][2].

• UNSPSC:

  12352005

• Target:

  Angiotensin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/sc-51316.html

• Smiles:

  O=C1N (CCCC) N=C (CCCC) N1CC2=CC=C (C3=C (C4=NN=NN4) C=CC=C3) C=C2

• Molecular Formula:

  C24H29N7O

• Molecular Weight:

  431.53

• References & Citations:

  [1]Olins GM, et al. In vitro pharmacology of a nonpeptidic angiotensin II receptor antagonist, SC-51316. J Pharmacol Exp Ther. 1992;261 (3) :1037-1043. |[2]Olins GM, et al. In vivo pharmacology of SC-51316, a nonpeptidic angiotensin II receptor antagonist. Am J Hypertens. 1993;6 (7 Pt 1) :619-625.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  133690-62-7