AZ'9567

• UNSPSC Description:

  AZ9567 is a potent MAT2A inhibitor. AZ9567 exhibits antiproliferative activity against MTAP KO HCT116 cells with a pIC50 of 8.9[1].

• Target Antigen:

  Methionine Adenosyltransferase (MAT)

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/az-9567.html

• Solubility:

  DMSO : 62.5 mg/mL (ultrasonic)

• Smiles:

  O=C1C(C2=CC3=CN(C)N=C3C=C2)=CC(NN=C4C5CC5)=C4N1C6=CC=C(OC(F)F)C=C6

• Molecular Weight:

  447.44

• References & Citations:

  [1]Atkinson SJ, et al. Development of a Series of Pyrrolopyridone MAT2A Inhibitors. J Med Chem. 2024 Mar 28;67(6):4541-4559.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported