AZ'9567

• Description :

  AZ9567 is a potent MAT2A inhibitor. AZ9567 exhibits antiproliferative activity against MTAP KO HCT116 cells with a pIC50 of 8.9[1].

• UNSPSC :

  12352005

• Target :

  Methionine Adenosyltransferase (MAT)

• Type :

  Reference compound

• Related Pathways :

  Epigenetics; Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/az-9567.html

• Purity :

  99.21

• Solubility :

  DMSO : 62.5 mg/mL (ultrasonic)

• Smiles :

  O=C1C(C2=CC3=CN(C)N=C3C=C2)=CC(NN=C4C5CC5)=C4N1C6=CC=C(OC(F)F)C=C6

• Molecular Formula :

  C24H19F2N5O2

• Molecular Weight :

  447.44

• References & Citations :

  [1]Atkinson SJ, et al. Development of a Series of Pyrrolopyridone MAT2A Inhibitors. J Med Chem. 2024 Mar 28;67 (6) :4541-4559.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3056570-19-2]