AZ-TAK1

CAT: 0804-HY-153320Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-153320Size:1 Each

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Description

AZ-TAK1, an ATP-competitive small molecule inhibitor of TAK1, dephosphorylates TAK1, p38, and IκB-α in lymphoma cell lines[1].

CAS Number

1413440-36-4

UNSPSC

12352005

Target

MAP3K

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/az-tak1.html

Solubility

10 mM in DMSO

Smiles

FC1=C(C2=CN=C3C=CC=NN32)N=C(NC4=CC(OCCN5CCC(CC5)O)=CC(CC)=C4)N=C1

Molecular Formula

C25H28FN7O2

Molecular Weight

477.53

References & Citations

[1]Daniela Buglio, et al. Essential role of TAK1 in regulating mantle cell lymphoma survival. Blood. 2012 Jul 12;120 (2) :347-55.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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