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AZ'6421

CAT: 0804-HY-135312-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-135312-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZ'6421 acts as Protcolysis Targeting Chimera (PROTAC) to selectively degrade estrogen receptor alpha. AZ'6421 has a potent anti-tumour effect to inhibit the uncontrolled cellular proliferation which arises from malignant disease. AZ'6421 can be used for the research of cancer such as breast cancer[1].
CAS Number
2361115-35-5
UNSPSC
12352005
Target
Estrogen Receptor/ERR; PROTACs
Type
Reference compound
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/az-6421.html
Purity
98.13
Solubility
DMSO : ≥ 100 mg/mL
Smiles
C[C@@H](N1CC(C)(F)C)CC2=C(NC3=C2C=CC=C3)[C@H]1C4=C(F)C=C(OCCCOCCCOCC(N[C@@H](C(C)(C)C)C(N5[C@H](C(NCC6=CC=C(C7=C(C)N=CS7)C=C6)=O)C[C@@H](O)C5)=O)=O)C=C4F
Molecular Formula
C52H65F3N6O7S
Molecular Weight
975.17
References & Citations
[1]Bin Yang, et al. Compounds and their use in treating cancer. Patent WO2019123367A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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