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VUF 10214

CAT: 0804-HY-119279Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-119279Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VUF 10214 is a H4 receptor ligand with a pKi of 8.25. VUF 10214 exhibits significant anti-inflammatory activity in a carrageenan-induced paw edema rat model and can be used for research in the field of inflammatory diseases[1].
CAS Number
848837-33-2
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/vuf-10214.html
Smiles
O=C1NC2=C(N=C1N3CCN(CC3)C)C=C(C(Cl)=C2)Cl
Molecular Formula
C13H14Cl2N4O
Molecular Weight
313.18
References & Citations
[1]Smits RA, et al. Fragment based design of new H4 receptor-ligands with anti-inflammatory properties in vivo. J Med Chem. 2008 Apr 24;51 (8) :2457-67.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H4 Receptor

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