VUF 8430 (dihydrobromide)

VUF 8430 (dihydrobromide)

• CAS Number: 100130-32-3
• UNSPSC Description: VUF 8430 (dihydrobromide) is a potent and selective histamine H4 receptor agonist with a Ki of 31.6 nM and an EC50 of 50 nM[1].
• Target Antigen: Histamine Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/vuf-8430-dihydrobromide.html
• Purity: 98.00
• Solubility: H2O : 125 mg/mL (ultrasonic)
• Smiles: N=C(N)SCCNC(N)=N.[H]Br.[H]Br
• Molecular Weight: 323.05
• References & Citations: [1]Lim HD, et al. Discovery of S-(2-guanidylethyl)-isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist. J Med Chem. 2006 Nov 16;49(23):6650-1.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported