VUF 8430

• UNSPSC Description:

  VUF 8430 is a potent and selective histamine H4 receptor agonist with a Ki of 31.6 nM and an EC50 of 50 nM[1].

• Target Antigen:

  Histamine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  neurological disease

• Assay Protocol:

  https://www.medchemexpress.com/vuf-8430.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC(SCCNC(N)=N)=N

• Molecular Weight:

  161.23

• References & Citations:

  [1]Lim HD, et al. Discovery of S-(2-guanidylethyl)-isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist. J Med Chem. 2006 Nov 16;49(23):6650-1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  98021-17-1