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VUF 8430

CAT: 0804-HY-108977Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-108977Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VUF 8430 is a potent and selective histamine H4 receptor agonist with a Ki of 31.6 nM and an EC50 of 50 nM[1].
CAS Number
[98021-17-1]
UNSPSC
12352211
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological disease
Assay Protocol
https://www.medchemexpress.com/vuf-8430.html
Solubility
10 mM in DMSO
Smiles
NC(SCCNC(N)=N)=N
Molecular Formula
C4H11N5S
Molecular Weight
161.23
References & Citations
[1]Lim HD, et al. Discovery of S- (2-guanidylethyl) -isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist. J Med Chem. 2006 Nov 16;49 (23) :6650-1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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