VUF-5574

CAT: 0804-HY-103189-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-103189-01Size:5 mg
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Description
VUF-5574 is a selective antagonist of adenosine A3 receptor with a Ki of 4.03 nM for the recombinant human receptor[1].
CAS Number
[280570-45-8]
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/vuf-5574.html
Purity
99.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=C2C=CC=CC2=NC(C3=CC=CN=C3)=N1)NC4=CC=CC=C4OC
Molecular Formula
C21H17N5O2
Molecular Weight
371.39
References & Citations
[1]van Muijlwijk-Koezen JE, et al. Isoquinoline and quinazoline urea analogues as antagonists for the human adenosine A (3) receptor. J Med Chem. 2000 Jun 1;43 (11) :2227-38.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Adenosine A3 receptor (A3R)

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