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3-Hydroxyquinine

CAT: 0804-HY-113322-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113322-01Size:1 mg
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Description
3-Hydroxyquinine is a metabolite of Quinidine. 3-Hydroxyquinine prevents ventricular fibrillation and ventricular tachycardia after coronary reperfusion in an isolated rat heart reperfusion arrhythmia model in a concentration-dependent manner. 3-Hydroxyquinine can be used in the study of cardiac arrhythmias[1].
CAS Number
53467-23-5
Product Name Alternative
3-Hydroxyquinidine
UNSPSC
12352005
Hazard Statement
H302
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/3-hydroxyquinine.html
Smiles
C=C[C@](C[N@@]1CC2)(O)[C@@H]2C[C@@H]1[C@@H](O)C3=CC=NC4=CC=C(OC)C=C34
Molecular Formula
C20H24N2O3
Molecular Weight
340.42
Precautions
P264-P270-P330-P501
References & Citations
[1]Vozeh S, et al. Antiarrhythmic activity of two quinidine metabolites in experimental reperfusion arrhythmia: relative potency and pharmacodynamic interaction with the parent drug[J]. Journal of Pharmacology and Experimental Therapeutics, 1987, 243 (1) : 297-301.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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