2-Hydroxyquinoline

• Description:

  2-Hydroxyquinoline is an inhibitor of α-glucosidase and α-amylase with IC50 values of 64.4 µg/mL and 130.5 µg/mL, respectively. 2-Hydroxyquinoline can be used in the study of diabetes[1].

• UNSPSC:

  12352200

• Hazard Statement:

  H302, H315, H318, H335

• Target:

  Amylases; Glycosidase

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/2-hydroxyquinoline.html

• Purity:

  99.89

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C1C=CC2=CC=CC=C2N1

• Molecular Formula:

  C9H7NO

• Molecular Weight:

  145.16

• Precautions:

  H302, H315, H318, H335

• References & Citations:

  [1]Hwa-Won Lee, et al. 2-Hydroxyquinoline and Its Structural Analogs Show Antidiabetic Effects against α-Amylase and α-Glucosidase. Journal of Applied Biological Chemistry (2015) 58 (1), 1-3.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Biochemical Assay Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  [59-31-4]