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BMPR1B Rabbit Polyclonal Antibody

CAT: 0992-R1311-4Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-R1311-4Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMPR1B is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. The BMPR1B receptor plays a role in the formation of middle and proximal phalanges. Mutations in this gene have been associated with primary pulmonary hypertension. In the chick embryo, it has been shown that BMPR1B is found in precartilaginous condensations.
CAS Number
9007-83-4
Product Name Alternative
Activin receptor like kinase 6 antibody Acvrlk6 antibody ALK 6 antibody ALK6 antibody alk6tr antibody BMP type-1B receptor antibody BMPR IB antibody BMPR-1B antibody Bmpr1b antibody BMPRIB antibody BMR1B_HUMAN antibody Bone morphogenetic protein receptor type 1B antibody Bone morphogenetic protein receptor type IB antibody Bone morphogenetic protein receptor type-1B antibody BR 1b antibody BR1b antibody CDw 293 antibody CDw293 antibody CDw293 antigen antibody CFK 43a antibody CFK43a antibody Serine/threonine receptor kinase antibody zALK 6 antibody zALK6 antibody
Abbreviation
BMP type-1B receptor,BMPR-1B
Swiss Prot
O00238 Human, P36898 Mouse
Cellular Locus
Cell membrane
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant protein within human BMPR1B aa 14-126.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
HepG2, SHG-44, human ovarian carcinoma tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1000;IHC-P: 1:100-1:500;IF-Cell: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 57kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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