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BMPR1A Rabbit Polyclonal Antibody

CAT: 0992-R1510-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-R1510-1Size:100 µL
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Description
Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Two type I receptors have been characterized, BMPR-IA (also designated SKR5, ALK-3, and BRK-1) and BMPR-IB (also designated ALK-6 and SKR 6), that bind to bone morphogenetic proteins (BMP)-2, BMP-4, and osteogenic protein (OP)-1 (also designated BMP-7). BMPR-IA and BMPR-IB are both expressed in human glioma cell lines. The type II receptor, BMPR-II, efficiently binds to OP-1 and BMP-2 and weakly binds BMP-4, and it is widely expressed in different tissues, including brain. The BMP receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morphogenesis in a dose dependent fashion.
CAS Number
9007-83-4
Product Name Alternative
10q23del antibody Activin A receptor type II like kinase 3 antibody Activin receptor like kinase 3 antibody Activin receptor-like kinase 3 antibody ACVRLK 3 antibody ACVRLK3 antibody ALK 3 antibody ALK-3 antibody ALK3 antibody BMP type-1A receptor antibody BMPR 1A antibody Bmpr antibody BMPR-1A antibody Bmpr1a antibody BMR1A_HUMAN antibody Bone morphogenetic protein receptor type IA antibody Bone morphogenetic protein receptor type IA precursor antibody Bone morphogenetic protein receptor type-1A antibody BR 1a antibody BR1a antibody CD 292 antibody CD292 antibody CD292 antigen antibody EC 2.7.11.30 antibody Serine threonine protein kinase receptor R5 antibody Serine threonine protein kinase receptor R5 precursor antibody Serine/threonine-protein kinase receptor R5 antibody SKR 5 antibody SKR5 antibody zBMPR IA antibody zBMPRIA antibody
Abbreviation
BMP type-1A receptor,BMPR-1A,ALK-3,SKR5
Swiss Prot
P36894 Human
Cellular Locus
Cell membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human BMPR1A aa 11-180/532.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
293 cell lysates, Hela, HepG2, SKOV-3, human liver carcinoma tissue, human kidney tissue, mouse skeletal muscle tissue, mouse smooth muscle tissue, mouse kidney tissue, Jurkat.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 60 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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