BMPR1A Rabbit Polyclonal Antibody

• Description:

  Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Two type I receptors have been characterized, BMPR-IA (also designated SKR5, ALK-3, and BRK-1) and BMPR-IB (also designated ALK-6 and SKR 6), that bind to bone morphogenetic proteins (BMP)-2, BMP-4, and osteogenic protein (OP)-1 (also designated BMP-7). BMPR-IA and BMPR-IB are both expressed in human glioma cell lines. The type II receptor, BMPR-II, efficiently binds to OP-1 and BMP-2 and weakly binds BMP-4, and it is widely expressed in different tissues, including brain. The BMP receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morphogenesis in a dose dependent fashion.

• Product Name Alternative:

  10q23del antibody Activin A receptor type II like kinase 3 antibody Activin receptor like kinase 3 antibody Activin receptor-like kinase 3 antibody ACVRLK 3 antibody ACVRLK3 antibody ALK 3 antibody ALK-3 antibody ALK3 antibody BMP type-1A receptor antibody BMPR 1A antibody Bmpr antibody BMPR-1A antibody Bmpr1a antibody BMR1A_HUMAN antibody Bone morphogenetic protein receptor type IA antibody Bone morphogenetic protein receptor type IA precursor antibody Bone morphogenetic protein receptor type-1A antibody BR 1a antibody BR1a antibody CD 292 antibody CD292 antibody CD292 antigen antibody EC 2.7.11.30 antibody Serine threonine protein kinase receptor R5 antibody Serine threonine protein kinase receptor R5 precursor antibody Serine/threonine-protein kinase receptor R5 antibody SKR 5 antibody SKR5 antibody zBMPR IA antibody zBMPRIA antibody

• Abbreviation:

  BMP type-1A receptor,BMPR-1A,ALK-3,SKR5

• Swiss Prot:

  P36894 Human

• Cellular Locus:

  Cell membrane.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein within human BMPR1A aa 11-180/532.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P, FC

• Positive Control:

  293 cell lysates, Hela, HepG2, SKOV-3, human liver carcinoma tissue, human kidney tissue, mouse skeletal muscle tissue, mouse smooth muscle tissue, mouse kidney tissue, Jurkat.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 60 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4