PSMC5 Rabbit Polyclonal Antibody

• Description :

  The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene.

• CAS Number :

  9007-83-4

• Product Name Alternative :

  26S protease regulatory subunit 8 antibody 26S proteasome AAA-ATPase subunit RPT6 antibody Cim3 antibody MSUG1 protein antibody p45 antibody p45/SUG antibody Proteasome 26S ATPase subunit 5 antibody Proteasome 26S subunit ATPase 5 antibody Proteasome prosome macropain 26S subunit ATPase 5 antibody Proteasome subunit p45 antibody PRS8_HUMAN antibody PSMC5 antibody Rpt6 antibody S8 antibody SUG1 antibody Tat binding protein homolog 10 antibody TBP10 antibody Thyroid hormone receptor interacting protein 1 antibody Thyroid hormone receptor-interacting protein 1 antibody Thyroid receptor interactor 1 antibody TRIP1 antibody TRIP1 (SUG1) antibody

• Abbreviation :

  PSMC5

• Swiss Prot :

  P62195 Human, P62196 Mouse, P62198 Rat

• Cellular Locus :

  Cytoplasm, Nucleus.

• Host :

  Rabbit

• Species Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant protein within Human PSMC5 aa 207-406 / 406.

• Isotype :

  IgG

• Conjugation :

  Non-conjugated

• Type :

  Rabbit polyclonal Antibody

• Applications :

  WB, IHC-P, IF-Cell

• Positive Control :

  A431 cell lysate, MCF-7 cell lysate, Hela cell lysate, HepG2 cell lysate, mouse testis tissue lysate, rat testis tissue lysate, rat brain tissue, human lung carcinoma tissue, A549, Hela.

• Concentration :

  2.13 mg/mL

• Dilution :

  WB: 1:1,000;IHC-P: 1:1,000;IF-Cell: 1:200

• Purity :

  Immunogen affinity purified.

• Form :

  Liquid

• Buffer :

  PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight :

  Predicted band size: 46 kDa

• Storage Conditions :

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody :

  No