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PSMC5 Rabbit Polyclonal Antibody

CAT: 0992-HA500423Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500423Size:100 µL
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Description
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene.
CAS Number
9007-83-4
Product Name Alternative
26S protease regulatory subunit 8 antibody 26S proteasome AAA-ATPase subunit RPT6 antibody Cim3 antibody MSUG1 protein antibody p45 antibody p45/SUG antibody Proteasome 26S ATPase subunit 5 antibody Proteasome 26S subunit ATPase 5 antibody Proteasome prosome macropain 26S subunit ATPase 5 antibody Proteasome subunit p45 antibody PRS8_HUMAN antibody PSMC5 antibody Rpt6 antibody S8 antibody SUG1 antibody Tat binding protein homolog 10 antibody TBP10 antibody Thyroid hormone receptor interacting protein 1 antibody Thyroid hormone receptor-interacting protein 1 antibody Thyroid receptor interactor 1 antibody TRIP1 antibody TRIP1 (SUG1) antibody
Abbreviation
PSMC5
Swiss Prot
P62195 Human, P62196 Mouse, P62198 Rat
Cellular Locus
Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human PSMC5 aa 207-406 / 406.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
A431 cell lysate, MCF-7 cell lysate, Hela cell lysate, HepG2 cell lysate, mouse testis tissue lysate, rat testis tissue lysate, rat brain tissue, human lung carcinoma tissue, A549, Hela.
Concentration
2.13 mg/mL
Dilution
WB: 1:1,000;IHC-P: 1:1,000;IF-Cell: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 46 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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