PSMC2 Rabbit Polyclonal Antibody

• Description:

  Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides. Expression is not cell cycle-dependent and occurs throughout the cell cycle.

• Product Name Alternative:

  26S protease complex antibody 26S protease regulatory subunit 7 antibody 26S proteasome AAA-ATPase subunit RPT1 antibody mammalian suppressor of sgv-1 of yeast antibody MSS1 antibody Nbla10058 antibody protease 26S subunit 7 antibody Proteasome 19S S7 antibody proteasome 26S ATPase subunit 2 antibody Proteasome 26S subunit ATPase 2 antibody Proteasome 26S subunit ATPase 2 antibody Protein MSS1 antibody PRS7_HUMAN antibody PSMC2 antibody putative protein product of Nbla10058 antibody S7 antibody

• Abbreviation:

  26S proteasome regulatory subunit 7 26S proteasome AAA-ATPase subunit RPT1 Proteasome 26S subunit ATPase 2 PSMC2 MSS1

• Swiss Prot:

  P35998 Human, P46471 Mouse, Q63347 Rat

• Cellular Locus:

  Cytoplasm

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein within human PSMC2 aa 2-251.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IF-Cell

• Positive Control:

  Hela cell lysate, HepG2 cell lysate, rat spleen tissue lysate, mouse spleen tissue lysate, SiHa.

• Concentration:

  1.70 mg/mL

• Dilution:

  WB: 1:500;IF-Cell: 1:200

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 49 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4