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PSMA5 Rabbit Polyclonal Antibody

CAT: 0992-ER2001-68Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER2001-68Size:100 µL
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Description
Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
CAS Number
9007-83-4
Product Name Alternative
Macropain zeta chain antibody Multicatalytic endopeptidase complex zeta chain antibody Proteasome (prosome macropain) subunit alpha type 5 antibody Proteasome alpha5 subunit antibody Proteasome component 5 antibody Proteasome subunit alpha type 5 antibody Proteasome subunit alpha type-5 antibody Proteasome subunit zeta antibody Proteasome zeta chain antibody PSA5_HUMAN antibody PSC5 antibody PSMA5 antibody ZETA antibody
Abbreviation
Proteasome subunit alpha type-5 Macropain zeta chain Multicatalytic endopeptidase complex zeta chain Proteasome zeta chain
Swiss Prot
P28066 Human, Q9Z2U1 Mouse, P34064 Rat
Cellular Locus
Cytoplasm, Nucleus, Proteasome.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human PSMA5 aa 1-200.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Hela cell lysate, 293 cell lysate, mouse cerebellum tissue lysate, mouse liver tissue lysate, rat liver tissue lysate, human liver carcinoma tissue, human colon carcinoma tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IHC-P: 1:100-1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
26 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No