Histamine H2 receptor Rabbit Polyclonal Antibody

Histamine H2 receptor Rabbit Polyclonal Antibody

• Description: The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway. Antagonists for this receptor have proven to be effective therapy for acid peptic disorders of the gastrointestinal tract. Certain antagonists are used in the treatment of neuropsychiatric and neurological diseases such as schizophrenia, Alzheimer disease and Parkinson disease.
• Product Name Alternative: Gastric receptor 1 antibody Gastric receptor I antibody H2R antibody HGNC:5183 antibody HH2R antibody Histamine H2 receptor antibody Histamine receptor H2 antibody HRH2 antibody HRH2_HUMAN antibody OTTHUMP00000161242 antibody OTTHUMP00000161243 antibody
• Abbreviation: Histamine H2 receptor H2R HH2R Gastric receptor I
• CAS Number: 9007-83-4
• Swiss Prot: P25021 Human
• Cellular Locus: Cell membrane, Membrane.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within human Histamine H2 receptor aa 300-359.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IHC-P
• Positive Control: PC-3M cell lysate, SHSY5Y cell lysate, human stomach tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:2,000;IHC-P: 1:50-1:200
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 40 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No