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IP3 Receptor Rabbit Polyclonal Antibody

CAT: 0992-ER1803-17Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1803-17Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.
CAS Number
9007-83-4
Product Name Alternative
4 antibody 5-trisphosphate receptor antibody 5-trisphosphate receptor type 1 antibody DKFZp313E1334 antibody DKFZp313N1434 antibody inositol 1 4 5 triphosphate receptor type 1 antibody Inositol 1 4 5 trisphosphate Receptor Type 1 antibody Inositol 1 antibody InsP3R1 antibody IP3 antibody IP3 receptor antibody IP3 receptor isoform 1 antibody IP3R 1 antibody IP3R antibody IP3R1 antibody ITPR 1 antibody Itpr1 antibody ITPR1_HUMAN antibody SCA15 antibody SCA16 antibody SCA29 antibody Type 1 inositol 1 4 5 trisphosphate receptor antibody Type 1 inositol 1 antibody Type 1 InsP3 receptor antibody
Abbreviation
IP3R 1, InsP3R1, Type 1 InsP3 receptor, ITPR1, INSP3R1
Swiss Prot
Q14643 Human, P11881 Mouse, P29994 Rat
Cellular Locus
Cytoplasm. Cytoplasmic vesicle. Endoplasmic reticulum. Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within C-terminal human IP3 Receptor.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Hela, rat brain tissue, mouse brain tissue, SH-SY-5Y.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:600 ;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 314 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No