Histamine H1 Receptor rabbit pAb | Gentaur

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Histamine H1 Receptor rabbit pAb

CAT:

855-ES2516-01

Size:

50 μL

Price:

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Histamine H1 Receptor rabbit pAb

Description: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by Ref
Synonyms: HRH1; Histamine H1 receptor; H1R; HH1R
Gene ID: 3269
UniProt: P35367
Cellular Locus: Cell membrane ; Multi-pass membrane protein.
Host: Rabbit
Species Reactivity: Human, Rat, Mouse,
Immunogen: The antiserum was produced against synthesized peptide derived from human HRH1. AA range:141-190
Clonality: Polyclonal
Validated Applications: WB, IF, ELISA
Stability: 1 year
Concentration: 1 mg/mL
Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight: 60kD
Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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