hnRNP K Recombinant Rabbit Monoclonal Antibody [SC60-03]

hnRNP K Recombinant Rabbit Monoclonal Antibody [SC60-03]

• Description: Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of poly-peptides that contribute to mRNA transcription and pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA Polymerase II. There are approximately 20 known hnRNP proteins and their complexes are the major constituents of the spliceosome. The majority of hnRNP protein are localized to the nucleus, however some shuttle between the nucleus and the cytoplasm, such as hnRNP K. hnRNP K recruits a variety of molecular partners through two K homologous (KH) domains, which are required for protein-protein interactions. hnRNP K also contains several potential phosphorylation sites, including Ser 302, the major site of PKCd phosphorylation, which are thought to regulate various cellular functions, including sequence-specific DNA binding, transcription, RNA binding and nucleocytoplasmic shuttling.
• Product Name Alternative: CSBP antibody dC stretch binding protein antibody FLJ41122 antibody Heterogeneous nuclear ribonucleoprotein K antibody hnRNP K antibody HNRNPK antibody HNRPK antibody HNRPK_HUMAN antibody Transformation up regulated nuclear protein antibody Transformation up-regulated nuclear protein antibody Transformation upregulated nuclear protein antibody TUNP antibody
• Abbreviation: hnRNP K, TUNP, HNRNPK
• CAS Number: 9000-83-3
• Swiss Prot: P61978 Human, P61979 Mouse, P61980 Rat
• Cellular Locus: Nucleoplasm, Cytoplasm, podosome
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human hnRNP K aa 1-49 / 463.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP
• Positive Control: HeLa cell lysate, PC-12 cell lysate, mouse thymus tissue lysate, rat thymus tissue lysate, Hela, HepG2, SKOV-3, human colon carcinoma tissue, mouse brain tissue, human breast carcinoma tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:5,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 51 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes