hnRNP A2B1 Recombinant Mouse Monoclonal Antibody [PSH06-47]

hnRNP A2B1 Recombinant Mouse Monoclonal Antibody [PSH06-47]

• Description: This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. HnRNPA2B1 is an autoantigen in autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus and mixed connective tissue disease. When referred to as an autoantigen, hnRNPA2B1 is also known as RA33.
• Product Name Alternative: Heterogeneous nuclear ribonucleoprotein A2 antibody Heterogeneous nuclear ribonucleoprotein A2/B1 antibody Heterogeneous nuclear ribonucleoprotein B1 antibody Heterogeneous nuclear ribonucleoproteins A2/B1 antibody hnRNP A2 / hnRNP B1 antibody hnRNP A2 antibody hnRNP A2/B1 antibody hnRNP B1 antibody hnRNP-A2 antibody hnRNP-B1 antibody hnRNPA2 antibody Hnrnpa2b1 antibody hnRNPB1 antibody HNRPA2 antibody HNRPA2B1 antibody HNRPB1 antibody Nuclear ribonucleoprotein particle A2 protein antibody RNP A2 antibody RNP B1 antibody RNP-A2 antibody RNP-B1 antibody RNPA2 antibody RNPB1 antibody ROA2_HUMAN antibody SNRPB1 antibody
• Abbreviation: HNRNPA2B1, HNRPA2B1
• CAS Number: 9000-83-3
• Swiss Prot: P22626 Human, O88569 Mouse, A7VJC2 Rat
• Cellular Locus: Nucleus, nucleoplasm, Cytoplasm, Cytoplasmic granule, Secreted, extracellular exosome.
• Host: Mouse
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within human hnRNP A2B1 aa 1-50.
• Isotype: IgG1
• Clone: PSH06-47
• Conjugation: Non-conjugated
• Type: Recombinant Mouse monoclonal Antibody
• Applications: WB, IHC-P, IF-Cell, FC, IF-Tissue
• Positive Control: HEK-293 cell lysate, HeLa cell lysate, MCF7 cell lysate, A431 cell lysate, K-562 cell lysate, A549 cell lysate, SK-Br-3 cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, PC-12 cell lysate, human colon tissue, human testis tissue, mouse colon tissue, mouse testis tissue, rat colon tissue, rat testis tissue, HEK-293, NIH/3T3.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P: 1:5,000 ;IF-Cell: 1:100 ;FC: 1:1,000 ;IF-Tissue: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 37 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes