Integrin beta 1 Mouse Monoclonal Antibody [B10-A5]

Integrin beta 1 Mouse Monoclonal Antibody [B10-A5]

• Description: Integrins are transmembrane receptors that mediate the attachment between a cell and its surroundings, such as other cells or the extracellular matrix (ECM). Integrins are obligate heterodimers containing two distinct chains, called the α (alpha) and β (beta) subunits. The molecular mass of the integrin subunits can vary from 90 kDa to 160 kDa. Beta subunits have four cysteine-rich repeated sequences. Both α and β subunits bind several divalent cations. Integrins have two main functions: Attachment of the cell to the ECM and signal transduction from the ECM to the cell. However, they are also involved in a wide range of other biological activities, including immune patrolling, cell migration, and binding to cells by certain viruses, such as adenovirus, echovirus, hantavirus, and foot and mouth disease viruses. Research studies have implicated β1 integrin in various activities including embryonic development, blood vessel, skin, bone, and muscle formation, as well as tumor metastasis and angiogenesis.
• Product Name Alternative: beta1 integrin antibody CD29 antibody Fibronectin receptor subunit beta antibody FNRB antibody Glycoprotein IIa antibody GP IIa antibody GPIIA antibody Integrin beta-1 antibody Integrin subunit beta 1 antibody integrin VLA-4 beta subunit antibody Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) antibody ITB1_HUMAN antibody ITGB1 antibody MDF2 antibody MSK12 antibody OTTHUMP00000019420 antibody Very late activation protein, beta polypeptide antibody VLA BETA antibody VLA-4 subunit beta antibody VLA-BETA antibody VLAB antibody VLAbeta antibody
• Abbreviation: GPIIA, CD29, FNRB, MDF2, MSK12, ITGB1
• CAS Number: 9007-83-4
• Swiss Prot: P05556 Human, P09055 Mouse
• Cellular Locus: Cell Membrane, Cell projection, Cleavage furrow.
• Host: Mouse
• Species Reactivity: Human, Mouse
• Immunogen: Synthetic peptide of the C-terminal Human Integrin beta 1.
• Isotype: IgM
• Conjugation: Non-conjugated
• Type: Mouse monoclonal Antibody
• Applications: WB, IHC-P, FC
• Positive Control: Human liver tissue lysate, mouse liver tissue lysate, A172 cell lysate, human tonsil tissue, human kidney tissue, L929.
• Concentration: 2 mg/mL
• Dilution: WB: 1:1000-1:5000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 88 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No