Integrin beta 1 Rabbit Polyclonal Antibody

Integrin beta 1 Rabbit Polyclonal Antibody

• Description: Integrin beta-1 (ITGB1), also known as CD29, is a cell surface receptor that in humans is encoded by the ITGB1 gene. This integrin associates with integrin alpha 1 and integrin alpha 2 to form integrin complexes which function as collagen receptors. It also forms dimers with integrin alpha 3 to form integrin receptors for netrin 1 and reelin. These and other integrin beta 1 complexes have been historically known as very late activation (VLA) antigens. Integrin beta 1 is expressed as at least four different isoforms. In cardiac muscle and skeletal muscle, the integrin beta-1D isoform is specifically expressed, and localizes to costameres, where it aids in the lateral force transmission from the Z-discs to the extracellular matrix. Abnormal levels of integrin beta-1D have been found in limb girdle muscular dystrophy and polyneuropathy.
• Product Name Alternative: beta1 integrin antibody CD29 antibody Fibronectin receptor subunit beta antibody FNRB antibody Glycoprotein IIa antibody GP IIa antibody GPIIA antibody Integrin beta-1 antibody integrin VLA-4 beta subunit antibody Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) antibody ITB1_HUMAN antibody ITGB1 antibody MDF2 antibody MSK12 antibody OTTHUMP00000019420 antibody Very late activation protein, beta polypeptide antibody VLA BETA antibody VLA-4 subunit beta antibody VLA-BETA antibody VLAB antibody VLAbeta antibody
• Abbreviation: GPIIA,ITB1
• CAS Number: 9007-83-4
• Swiss Prot: P05556 Human, P09055 Mouse
• Cellular Locus: Cell membrane, cytoplasm
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Synthetic peptide within residues of Integrin beta-1 aa 749-798 / 798.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IHC-P, FC
• Positive Control: Human liver, human kidney, NIH/3T3, A172, Hela, human liver carcinoma tissue, human colon carcinoma tissue, HepG2.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:1,000 ;FC: 1:100 ;IHC-P: 1:200
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 88 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: No