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Integrin beta 1 Rabbit Polyclonal Antibody

CAT: 0992-ER31001Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER31001Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Integrin beta-1 (ITGB1), also known as CD29, is a cell surface receptor that in humans is encoded by the ITGB1 gene. This integrin associates with integrin alpha 1 and integrin alpha 2 to form integrin complexes which function as collagen receptors. It also forms dimers with integrin alpha 3 to form integrin receptors for netrin 1 and reelin. These and other integrin beta 1 complexes have been historically known as very late activation (VLA) antigens. Integrin beta 1 is expressed as at least four different isoforms. In cardiac muscle and skeletal muscle, the integrin beta-1D isoform is specifically expressed, and localizes to costameres, where it aids in the lateral force transmission from the Z-discs to the extracellular matrix. Abnormal levels of integrin beta-1D have been found in limb girdle muscular dystrophy and polyneuropathy.
CAS Number
9007-83-4
Product Name Alternative
beta1 integrin antibody CD29 antibody Fibronectin receptor subunit beta antibody FNRB antibody Glycoprotein IIa antibody GP IIa antibody GPIIA antibody Integrin beta-1 antibody integrin VLA-4 beta subunit antibody Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) antibody ITB1_HUMAN antibody ITGB1 antibody MDF2 antibody MSK12 antibody OTTHUMP00000019420 antibody Very late activation protein, beta polypeptide antibody VLA BETA antibody VLA-4 subunit beta antibody VLA-BETA antibody VLAB antibody VLAbeta antibody
Abbreviation
GPIIA,ITB1
Swiss Prot
P05556 Human, P09055 Mouse
Cellular Locus
Cell membrane, cytoplasm
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within residues of Integrin beta-1 aa 749-798 / 798.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Human liver, human kidney, NIH/3T3, A172, Hela, human liver carcinoma tissue, human colon carcinoma tissue, HepG2.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;FC: 1:100 ;IHC-P: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 88 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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