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Integrin beta 3 Rabbit Polyclonal Antibody

CAT: 0992-ER1601-4Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1601-4Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
CAS Number
9007-83-4
Product Name Alternative
Antigen identified by monoclonal antibody L230 antibody CD 51 antibody CD 61 antibody CD51 antibody CD51 antigen antibody CD61 antibody CD61 antigen antibody DKFZp686A08142 antibody GP3A antibody GPIIIa antibody Integrin alpha V antibody Integrin alpha V vitronectin receptor alpha polypeptide antibody Integrin alpha V vitronectin receptor alpha polypeptide antigen CD51 antibody integrin alpha-V antibody Integrin alpha-V light chain antibody Integrin beta 3 antibody Integrin beta 3 platelet glycoprotein IIIa antigen CD61 antibody Integrin beta chain beta 3 antibody integrinVbeta3 antibody ITAV_HUMAN antibody ITGAV antibody ITGB 3 antibody ITGB3 antibody MSK 8 antibody MSK8 antibody Platelet glycoprotein IIIa antibody Platelet glycoprotein IIIa precursor antibody Platelet membrane glycoprotein IIIa antibody Vitronectin receptor alpha polypeptide antibody vitronectin receptor antibody Vitronectin receptor subunit alpha antibody VNR 1 antibody VNR1 antibody VNRA antibody
Abbreviation
GPIIIa, ITGB3, GP3A
Swiss Prot
P05106 Human, O54890 Mouse
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human Integrin beta-3 aa 481-530 / 788.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
A431, rat spleen tissue lysate, rat ossature tissue, human tonsil tissue, human kidney tissue, human placenta tissue, mouse kidney tissue, HUVEC.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
87/110 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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