PF-9363

• Description :

  PF-9363 (CTx-648) is a first-in-class potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer[1][2].

• Product Name Alternative :

  CTx-648

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319

• Target :

  Histone Acetyltransferase

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/pf-9363.html

• Purity :

  99.64

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  O=S(C1=C(OC)C=CC=C1OC)(NC2=NOC3=C2C(OC)=CC(CN4N=CC=C4)=C3)=O

• Molecular Formula :

  C20H20N4O6S

• Molecular Weight :

  444.46

• Precautions :

  H302, H315, H319

• References & Citations :

  [1]Shikhar S, et al. First-in-class KAT6A/KAT6B Inhibitor CTx-648 (PF-9363) Demonstrates Potent Anti-tumor Activity in ER+ Breast Cancer with KAT6A Dysregulation|[2]WO2020254946

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  MOZ/MORF

• CAS Number :

  [2569009-58-9]