PF-9363

• Description:

  PF-9363 (CTx-648) is a first-in-class potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer[1][2].

• Product Name Alternative:

  CTx-648

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319

• Target:

  Histone Acetyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pf-9363.html

• Purity:

  99.64

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=S(C1=C(OC)C=CC=C1OC)(NC2=NOC3=C2C(OC)=CC(CN4N=CC=C4)=C3)=O

• Molecular Formula:

  C20H20N4O6S

• Molecular Weight:

  444.46

• Precautions:

  H302, H315, H319

• References & Citations:

  [1]Shikhar S, et al. First-in-class KAT6A/KAT6B Inhibitor CTx-648 (PF-9363) Demonstrates Potent Anti-tumor Activity in ER+ Breast Cancer with KAT6A Dysregulation|[2]WO2020254946

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  MOZ/MORF

• CAS Number:

  [2569009-58-9]