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6β-Hydroxy Eplerenone

CAT: 0804-HY-137396Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-137396Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
6β-Hydroxy Eplerenone is a metabolite of Eplerenone. 6β-Hydroxy Eplerenone plays an important role in the research of hypertension, atherosclerosis, chronic systolic heart failure (HF) and cardiovascular (CV).
CAS Number
209253-80-5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/6β-hydroxy-eplerenone.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@]34[C@]([C@@H]([C@H](C1=CC(CC2)=O)O)C(OC)=O)([H])[C@@]5([H])[C@](C[C@@]3([H])O4)([C@]6(CCC(O6)=O)CC5)C
Molecular Formula
C24H30O7
Molecular Weight
430.49
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Chyung S Cook, et al. Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: differential metabolism by CYP3A4 and CYP3A5. Drug Metab Dispos. 2002 Dec;30 (12) :1344-51.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported