Products for Research Use Only
RegisterLogin

6-Hydroxy bexarotene

CAT: 0804-HY-126044-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-126044-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
6-Hydroxy bexarotene is the main circulating metabolite of bexarotene, found in rats, dogs, and humans. Compared to the parent compound, 6-hydroxy-bexarotene shows a significantly reduced ability to bind to retinoid receptors and exhibits very minimal activity in activating retinoic acid receptors[1].
CAS Number
368451-07-4
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/6-hydroxy-bexarotene.html
Smiles
CC1=CC2=C(C(C)(CC(C2(C)C)O)C)C=C1C(C3=CC=C(C=C3)C(O)=O)=C
Molecular Formula
C24H28O3
Molecular Weight
364.48
References & Citations
[1]S R Howell, et al. Bexarotene metabolism in rat, dog, and human, synthesis of oxidative metabolites, and in vitro activity at retinoid receptors. Drug Metab Dispos. 2001 Jul;29 (7) :990-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-14171-01Bexarotene
HY-W777169-01Bexarotene-13C4
HY-CE01228Bexarotene-CoA
HY-14171R-01Bexarotene (Standard)
HY-14171S2Bexarotene-13C6
HY-14171S-01Bexarotene-d4
HY-114744-016α-Hydroxy metandienone
HY-1373966β-Hydroxy Eplerenone
HY-110286-016-Hydroxy-DOPA
HY-137197-016β-Hydroxy dexamethasone

Alternative Products

CatalogName
FH23916-016-Hydroxy bexarotene
TRC-H817502-100MG6-Hydroxy Bexarotene-d3
TRC-H817505-250MG7-Hydroxy Bexarotene
TRC-H212210-50MG2-Hydroxy-bexarotene
4396907-Hydroxy Bexarotene-d6
4388666-Oxo Bexarotene
RM-B350006-01Bexarotene Impurity 6
AR-B01556-016-oxo-Bexarotene
TRC-H212205-100MG2-Hydroxy Methyl Ester Bexarotene
217219Bexarotene (4- (1- (3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl) vinyl) benzoic Acid) discontinued. See B1085-32C

Popular Products