6-Hydroxy-DOPA

• Description :

  6-Hydroxy-DOPA is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  DNA/RNA Synthesis

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/6-hydroxy-dopa.html

• Purity :

  98.37

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  OC(C(N)CC1=C(C=C(O)C(O)=C1)O)=O

• Molecular Formula :

  C9H11NO5

• Molecular Weight :

  213.19

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Chandramouly G, et al. Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers. Chem Biol. 2015;22 (11) :1491-1504.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [21373-30-8]