6-Hydroxy-DOPA

• Description:

  6-Hydroxy-DOPA is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  DNA/RNA Synthesis

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/6-hydroxy-dopa.html

• Purity:

  98.37

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  OC (C (N) CC1=C (C=C (O) C (O) =C1) O) =O

• Molecular Formula:

  C9H11NO5

• Molecular Weight:

  213.19

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Chandramouly G, et al. Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers. Chem Biol. 2015;22 (11) :1491-1504.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  21373-30-8