6-Hydroxy-DOPA

• UNSPSC Description:

  6-Hydroxy-DOPA is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer[1].

• Target Antigen:

  DNA/RNA Synthesis

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/6-hydroxy-dopa.html

• Purity:

  95.23

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  OC(C(N)CC1=C(C=C(O)C(O)=C1)O)=O

• Molecular Weight:

  213.19

• References & Citations:

  [1]Chandramouly G, et al. Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers. Chem Biol. 2015;22(11):1491-1504.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  21373-30-8