6β-Hydroxy dexamethasone

• Description :

  6β-Hydroxy dexamethasone is an active metabolite of the synthetic glucocorticoid Dexamethasone (HY-14648) [1].

• UNSPSC :

  12352211

• Target :

  Glucocorticoid Receptor

• Related Pathways :

  Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Smiles :

  O=C1C=C[C@]2(C([C@@H](C[C@@]3([C@@]2([C@H](C[C@]4([C@]3(C[C@H]([C@@]4(C(CO)=O)O)C)[H])C)O)F)[H])O)=C1)C

• Molecular Formula :

  C22H29FO6

• Molecular Weight :

  408.46

• References & Citations :

  [1]Gentile DM, et al. Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation. J Pharmacol Exp Ther. 1996 Apr;277 (1) :105-12.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [55879-47-5]