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HDAC8 ligand 1

CAT: 0804-HY-168176Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168176Size:1 Each
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Description
HDAC8 ligand 1 is a PROTAC target protein-ligand of PROTAC HDAC8 Degrader-2.
UNSPSC
12352005
Target
HDAC; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac8-ligand-1.html
Smiles
O=C(C1=CN=C(N2CCN(CC3=CN(C)C4=C3C=C(OCC(O)=O)C=C4)CC2)N=C1)NO
Molecular Formula
C21H24N6O5
Molecular Weight
440.45
References & Citations
[1]Hany S Ibrahim, et al. Probing class I histone deacetylases (HDAC) with proteolysis targeting chimera (PROTAC) for the development of highly potent and selective degraders. Bioorg Chem. 2024 Oct 12:153:107887.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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