PRMT5-IN-2

• Description:

  PRMT5-IN-2 is a rotein arginine methyltransferase 5 (PRMT5) inhibitor extracted from patent WO2018130840A1, compound 3[1].

• UNSPSC:

  12352005

• Target:

  Histone Methyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/prmt5-in-2.html

• Purity:

  98.68

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  O[C@H]1[C@@H](O[C@@]([C@@H](C2=CC(F)=C(Cl)C=C2)O)([H])[C@H]1O)N3C4=NC=NC(N)=C4C=C3

• Molecular Formula:

  C17H16ClFN4O4

• Molecular Weight:

  394.78

• References & Citations:

  [1]Pedro BELTRAN-ALVAREZ, et al. Arginine methylation inhibitor for treating or preventing cardiovascular disease. WO2018130840A1.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PRMT5

• CAS Number:

  [1989620-04-3]