Calpain-1 substrate, fluorogenic

• UNSPSC Description:

  Calpain-1 substrate, fluorogenic serves as a sensitive and specific substrate for calpain-1 that cleaves Tyr-Gly bond and results in enhanced fluorescence[1].(Ex/Em = 490 nm/518 nm)

• Target Antigen:

  Fluorescent Dye

• Type:

  Peptides

• Related Pathways:

  Others

• Field of Research:

  others

• Assay Protocol:

  https://www.medchemexpress.com/calpain-1-substrate-fluorogenic.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1OC2(C3=CC=C(O)C=C3OC4=CC(O)=CC=C42)C5=CC=C(C(NCCCC[C@H](N)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@H](C(NCC(N[C@@H](CCSC)C(N[C@@H](CCSC)C(N[C@H](C(O)=O)CCCCNC(C6=CC=C(C=C6)/N=N/C7=CC=C(C=C7)N(C)C)=O)=O)=O)=O)=O)CC8=CC=C(C=C8)O)=O)=O)=O)=O)C=C51

• Molecular Weight:

  1594.81

• References & Citations:

  [1]Sharon Dewitt, et al. Calpain Activation by Ca2+ and Its Role in Phagocytosis. Adv Exp Med Biol. 2020:1246:129-151.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  636566-40-0