Calpain-1 substrate, fluorogenic

• Description :

  Calpain-1 substrate, fluorogenic serves as a sensitive and specific substrate for calpain-1 that cleaves Tyr-Gly bond and results in enhanced fluorescence[1]. (Ex/Em = 490 nm/518 nm)

• UNSPSC :

  12352209

• Target :

  Fluorescent Dye

• Type :

  Peptides

• Related Pathways :

  Others

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/calpain-1-substrate-fluorogenic.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1OC2(C3=CC=C(O)C=C3OC4=CC(O)=CC=C42)C5=CC=C(C(NCCCC[C@H](N)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@H](C(NCC(N[C@@H](CCSC)C(N[C@@H](CCSC)C(N[C@H](C(O)=O)CCCCNC(C6=CC=C(C=C6)/N=N/C7=CC=C(C=C7)N(C)C)=O)=O)=O)=O)=O)CC8=CC=C(C=C8)O)=O)=O)=O)=O)C=C51

• Molecular Formula :

  C79H95N13O19S2

• Molecular Weight :

  1594.81

• References & Citations :

  [1]Sharon Dewitt, et al. Calpain Activation by Ca2+ and Its Role in Phagocytosis. Adv Exp Med Biol. 2020:1246:129-151.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [636566-40-0]