Cathepsin D/E Substrate, Fluorogenic

• UNSPSC Description:

  Cathepsin D/E Substrate, Fluorogenic, 11 amino acid peptide, is a selective substrate for cathepsins D and E. Cathepsin D/E Substrate, Fluorogenic does not act as a substrate for cathepsins B, H, or L[1].

• Target Antigen:

  Cathepsin

• Type:

  Peptides

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cathepsin-d-e-substrate-fluorogenic.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N[C@@H](CCCCN)C(N1[C@@H](CCC1)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCNC4=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C4)C(N[C@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC(C5=CC=C(OC)C=C5O6)=CC6=O

• Molecular Weight:

  1698.96

• References & Citations:

  [1]Mariela Nunez Santos, et al. Progranulin-derived granulin E and lysosome membrane protein CD68 interact to reciprocally regulate their protein homeostasis. J Biol Chem. 2022 Sep;298(9):102348.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported