Cathepsin D/E Substrate, Fluorogenic

CAT: 0804-HY-P10008Size: InquireDry Ice: NoHazardous: No
CAT#:0804-HY-P10008Size:Inquire
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UNSPSC Description
Cathepsin D/E Substrate, Fluorogenic, 11 amino acid peptide, is a selective substrate for cathepsins D and E. Cathepsin D/E Substrate, Fluorogenic does not act as a substrate for cathepsins B, H, or L[1].
Target Antigen
Cathepsin
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cathepsin-d-e-substrate-fluorogenic.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CCCCN)C(N1[C@@H](CCC1)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCNC4=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C4)C(N[C@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC(C5=CC=C(OC)C=C5O6)=CC6=O
Molecular Weight
1698.96
References & Citations
[1]Mariela Nunez Santos, et al. Progranulin-derived granulin E and lysosome membrane protein CD68 interact to reciprocally regulate their protein homeostasis. J Biol Chem. 2022 Sep;298(9):102348.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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