β-Secretase Substrate-1, Fluorogenic

• Description :

  β-Secretase Substrate-1, Fluorogenic is a fluorogenic substrate of β-Secretase that can be used to test β-Secretase activity[1].

• UNSPSC :

  12352209

• Target :

  Amyloid-β; Beta-secretase; Biochemical Assay Reagents

• Type :

  Peptides

• Related Pathways :

  Neuronal Signaling; Others

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/β-secretase-substrate-1-fluorogenic.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(CC1=CC(OC2=C1C=CC(OC)=C2)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCCCNC3=C(C=CC([N+]([O-])=O)=C3)[N+]([O-])=O)=O)CC4=CC=CC=C4)=O)CCC(O)=O)=O)C)=O)CC(O)=O)=O)CCSC)=O)CCCCN)=O)C(C)C)=O)CCC(O)=O

• Molecular Formula :

  C66H88N14O23S

• Molecular Weight :

  1477.55

• References & Citations :

  [1]Ye S, et, al. Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: apoE structure as a potential therapeutic target. Proc Natl Acad Sci U S A. 2005 Dec 20;102 (51) :18700-5.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported