α-Secretase Substrate, Fluorogenic

• UNSPSC Description:

  α-Secretase Substrate, Fluorogenic is α-secretase fluorogenic substrate that can be used to test α-secretase activity[1].

• Target Antigen:

  Others

• Type:

  Peptides

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/α-secretase-substrate-fluorogenic.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](C)C(N[C@@H](CCCCNC4=CC=C(C=C4[N+]([O-])=O)[N+]([O-])=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC5=CC(OC6=C5C=CC(OC)=C6)=O

• Molecular Weight:

  1499.62

• References & Citations:

  [1]Fukumoto H, et, al. A noncompetitive BACE1 inhibitor TAK-070 ameliorates Abeta pathology and behavioral deficits in a mouse model of Alzheimer's disease. J Neurosci. 2010 Aug 18;30(33):11157-66.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported