α-Secretase Substrate II, Fluorogenic

• Description :

  α-Secretase Substrate II, Fluorogenic is an internally quenched fluorogenic peptide substrate for α-Secretase that contains the α-secretase cleavage site of β-Amyloid precursor protein (APP) [1].Ex/Em = 340/490 nm

• UNSPSC :

  12352209

• Target :

  Fluorescent Dye

• Type :

  Peptides

• Related Pathways :

  Others

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/α-secretase-substrate-ii-fluorogenic.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)CCCCNC(C1=CC=C(C=C1)/N=N/C2=CC=C(C=C2)N(C)C)=O)=O)CC3=CC=CC=C3)=O)C(C)C)=O)CC(C)C)=O)CCCCN)=O)CCC(N)=O)=O)CC4=CNC=N4)=O)CC5=CNC=N5)=O)C(C)C)=O)CCC(NCCNC6=CC=CC7=C(C=CC=C67)S(=O)(O)=O)=O)=O)CCCNC(N)=N

• Molecular Formula :

  C100H144N30O20S

• Molecular Weight :

  2118.47

• References & Citations :

  [1]Marian Bienstein, et al. In Silico and Experimental ADAM17 Kinetic Modeling as Basis for Future Screening System for Modulators. Int J Mol Sci. 2022 Jan 25;23 (3) :1368.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported