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α-Secretase Substrate II, Fluorogenic

CAT: 0804-HY-P10163Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P10163Size:1 Each
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Description
α-Secretase Substrate II, Fluorogenic is an internally quenched fluorogenic peptide substrate for α-Secretase that contains the α-secretase cleavage site of β-Amyloid precursor protein (APP) [1].Ex/Em = 340/490 nm
UNSPSC
12352209
Target
Fluorescent Dye
Type
Peptides
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/α-secretase-substrate-ii-fluorogenic.html
Solubility
10 mM in DMSO
Smiles
O=C(C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)CCCCNC(C1=CC=C(C=C1)/N=N/C2=CC=C(C=C2)N(C)C)=O)=O)CC3=CC=CC=C3)=O)C(C)C)=O)CC(C)C)=O)CCCCN)=O)CCC(N)=O)=O)CC4=CNC=N4)=O)CC5=CNC=N5)=O)C(C)C)=O)CCC(NCCNC6=CC=CC7=C(C=CC=C67)S(=O)(O)=O)=O)=O)CCCNC(N)=N
Molecular Formula
C100H144N30O20S
Molecular Weight
2118.47
References & Citations
[1]Marian Bienstein, et al. In Silico and Experimental ADAM17 Kinetic Modeling as Basis for Future Screening System for Modulators. Int J Mol Sci. 2022 Jan 25;23 (3) :1368.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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