α-Secretase Substrate II, Fluorogenic

• UNSPSC Description:

  α-Secretase Substrate II, Fluorogenic is an internally quenched fluorogenic peptide substrate for α-Secretase that contains the α-secretase cleavage site of β-Amyloid precursor protein (APP)[1].Ex/Em = 340/490 nm

• Target Antigen:

  Fluorescent Dye

• Type:

  Peptides

• Related Pathways:

  Others

• Field of Research:

  others

• Assay Protocol:

  https://www.medchemexpress.com/α-secretase-substrate-ii-fluorogenic.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)CCCCNC(C1=CC=C(C=C1)/N=N/C2=CC=C(C=C2)N(C)C)=O)=O)CC3=CC=CC=C3)=O)C(C)C)=O)CC(C)C)=O)CCCCN)=O)CCC(N)=O)=O)CC4=CNC=N4)=O)CC5=CNC=N5)=O)C(C)C)=O)CCC(NCCNC6=CC=CC7=C(C=CC=C67)S(=O)(O)=O)=O)=O)CCCNC(N)=N

• Molecular Weight:

  2118.47

• References & Citations:

  [1]Marian Bienstein, et al. In Silico and Experimental ADAM17 Kinetic Modeling as Basis for Future Screening System for Modulators. Int J Mol Sci. 2022 Jan 25;23(3):1368.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported