MMP-8/MMP-26 Fluorogenic substrate

• UNSPSC Description:

  MMP-8/MMP-26 Fluorogenic substrate (DNP-Pro-Leu-Ala-Tyr-Trp-Ala-Arg) is a matrix metalloproteinase-8 (MMP-8) fluorogenic substrate. MMP-8/MMP-26 Fluorogenic substrate can be used for the research of atherosclerosis, pulmonary fibrosis, and sepsis[1].

• Target Antigen:

  MMP

• Type:

  Peptides

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/mmp-8-mmp-26-fluorogenic-substrate.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@H]1N(C(C=CC([N](=O)=O)=C2)=C2[N](=O)=O)CCC1)N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N[C@@H](C)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)CC3=CNC4=CC=CC=C34)=O)CC(C=C5)=CC=C5O)=O)=O

• Molecular Weight:

  1042.10

• References & Citations:

  [1]Morla S, et al. Discovery of Sulfated Small Molecule Inhibitors of Matrix Metalloproteinase-8. Biomolecules. 2020 Aug 9;10(8):1166.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  135662-05-4