ONO-8809

• Description:

  ONO-8809 is a Thromboxane A2 receptor antagonist. ONO-8809 inhibits the LTC4-induced airway hyperresponsiveness to histamine in a dose-dependent manner[1].

• UNSPSC:

  12352005

• Target:

  Histamine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ono-8809.html

• Smiles:

  O=S(NC[C@H]1[C@@H]([C@]2([H])C[C@@]1([H])CC2)/C=C\CCCC(OCCCCCCCCCC)=O)(C3=CC=C(C=C3)Br)=O

• Molecular Formula:

  C30H46BrNO4S

• Molecular Weight:

  596.66

• References & Citations:

  [1]Kurosawa M, et al. Inhibition of bronchial hyperresponsiveness to histamine induced by intravenous administration of leukotriene C4 by novel thromboxane A2 receptor antagonists ONO-NT-126 and ONO-8809 in guinea-pigs. Clin Exp Allergy. 1993 Oct;23 (10) :843-50.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [123288-47-1]