ONO 2050297

• Description :

  ONO 2050297 (Compound 19) is a selective Cysteinyl leukotriene (CysLT) antagonist with IC50s of 17 and 0.87 nM for CysLT1 and CysLT2, respectively. ONO 2050297 can be used for bronchial asthma research[1].

• UNSPSC :

  12352005

• Target :

  Leukotriene Receptor

• Related Pathways :

  GPCR/G Protein

• Field of Research :

  Inflammation/Immunology

• Smiles :

  O=C([C@H]1OC2=C(NC(C3=CC=C(OCCCCC4=CC=CC=C4)C=C3)=O)C=CC=C2N(CCCC(O)=O)C1)O

• Molecular Formula :

  C30H32N2O7

• Molecular Weight :

  532.58

• References & Citations :

  [1]Itadani S, et al. Discovery of Highly Potent Dual CysLT1 and CysLT2 Antagonist. ACS Med Chem Lett. 2014 Oct 6;5 (11) :1230-4.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  LTC4/CysLT2; LTD4/CysLT1

• CAS Number :

  [847655-65-6]