ONO-9517601

CAT: 0804-HY-179004Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-179004Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
ONO-9517601 is a potent, orally active, selective and CNS penetrant dual TREK-1/TREK-2 inhibitor (TREK-1 IC50= 0.067 μM, TREK-2 IC50= 0.23 μM) . ONO-9517601 displays robust efficacy in an MK-801 (HY-15084B) challenge rat novel object recognition (NOR) paradigm. ONO-9517601 can be used for research on neurological and cognitive disorders[1].
CAS Number
[2640753-22-4]
Product Name Alternative
VU6022856
UNSPSC
12352005
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease
Smiles
CC1=C(N=CC(C#CC2=CC=CC=C2)=C1)NC(C3=C(C=NN3C4CCN(CC4)C(C)=O)Cl)=O
Molecular Formula
C25H24ClN5O2
Molecular Weight
461.94
References & Citations
[1]Tanaka M, et al. Optimization of Selective and CNS Penetrant Alkyne-Based TREK Inhibitors: The Discovery and Characterization of ONO-9517601 (VU6022856) and ONO-7927846 (VU6024391) . J Med Chem. 2025;68 (21) :23554-23572.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-19101-01ONO-3307
HY-123816ONO 2050297
HY-117444-01ONO-9780307
HY-112788-01ONO-8590580
HY-150204-01ONO-0740556
HY-164517ONO-7579
HY-106961-01ONO 1301
HY-114841-01ONO 207
HY-123542ONO-3403
HY-113635ONO-6240

Alternative Products

CatalogName
MBS3846754-01ONO-7475
M20753-01ONO-7300243
M16307-01ONO-5334
MBS3604373-01ONO-6126
MBS3602659-01ONO-1301
MBS5815245ONO-0740556
MBS5802265ONO 4817
MBS5802334ONO-8711
MBS5777932Ono 1082
MBS5777933Ono 1301

Popular Products