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UR-7247

CAT: 0804-HY-117805Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-117805Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UR-7247 is a potent and orally active angiotensin II AT1 receptor antagonist. UR-7247 decreases arterial pressure and increases renal blood flow[1][2].
CAS Number
177847-28-8
UNSPSC
12352005
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ur-7247.html
Smiles
O=C(O)C1=C(N(N=C1C(C)C)CCC)CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=NN4
Molecular Formula
C24H26N6O2
Molecular Weight
430.50
References & Citations
[1]Maillard MP, et al. Pharmacologic profile of UR-7247, an orally active angiotensin II AT1 receptor antagonist, in healthy volunteers. p6. J Cardiovasc Pharmacol. 2000 Mar;35 (3) :383-9.|[2]Alexander Scriabine, et al. New Cardiovascular Drugs, XIIIth International Congress of Pharmacology, Munich, Germany, July 26-31, 1998. 16 (3) :312-317.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AT1 Receptor

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