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UR-AK49

CAT: 0931-T201412-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201412-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
902154-32-9
Target
PI3K, Apoptosis, Histamine Receptor, Akt, TRP/TRPV Channel
Related Pathways
PI3K/Akt/mTOR signaling, Membrane transporter/Ion channel, Immunology/Inflammation, Cytoskeletal Signaling, GPCR/G Protein, Neuroscience, Apoptosis
Bioactivity
UR-AK49 (compound 11) is an agonist for the human histamine H1 and H2 receptors. It exhibits an EC50 of 23 nM in the GTPase assay involving hH2R-Gsalpha fusion protein expressed in Sf9 insect cells. UR-AK49 is applicable in neurologically related research.
Smiles
O=C(NC(=N)NCCCC1=CN=CN1)CCC2CCCCC2
Molecular Formula
C16H27N5O
Molecular Weight
305.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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