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UR-MB-355

CAT: 0804-HY-157013Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157013Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UR-MB-355, a GPR3 ligand, binds to GPR3 and closely related receptors, GPR6 and GPR12, with similar submicromolar affinities[1].
UNSPSC
12352005
Target
GPR6
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ur-mb-355.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC(OC(C)C)=C(C=C1)CNC2=CC(C3=CC=CC=C3OCCCCCCNC(C4=CC(C([O-])=O)=C(C=C4)C5=C6C=CC(N(C)C)=CC6=[O+]C7=C5C=CC(N(C)C)=C7)=O)=NC8=NC=NN28.O=C(O)C(F)(F)F
Molecular Formula
C54H54ClF3N8O8
Molecular Weight
1035.50
References & Citations
[1]Merlin Bresinsky, et al. Development of Fluorescent AF64394 Analogues Enables Real-Time Binding Studies for the Orphan Class A GPCR GPR3. J Med Chem. 2023 Nov 9;66 (21) :15025-15041.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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